Marseille 2007
| Abstract #695 - STD Control for HIV Prevention: Current Evidence and Future Directions. | ||||
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Session: 27.7: Plenary (Plenary) on Tuesday @ 08.30-10.30 in HC, Auditorium/Overflow Chaired by Frans van den Boom, Susan Kippax, Benjamin Coriat Authors: Presenting Author: Dr John Douglas - CDC, United States |
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| Aim: A large body of epidemiologic and biologic evidence supports the premise that sexually transmitted diseases (STD) increase transmission of HIV infection through both enhanced susceptibility and infectivity. Community randomized trials of the effect of STD control on HIV prevention have produced varied results, likely because of differences in rates of curable STD and the phase of the HIV epidemic, and impact appears to be greatest in settings with high prevalence of curable bacterial genital ulcer disease (eg, syphilis, chancroid) and early HIV epidemics. In more advanced HIV epidemics, a growing body of evidence indicates that HSV-2 is the STI with the greatest impact on HIV transmission, and strategies directed to HSV-2 control (eg, suppressive antiviral therapy, lesion recognition and early treatment) offer promise of new HIV prevention approaches. | ||||
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