Marseille 2007
| Abstract #524 - Treatment Adherence - precision in concepts refines understanding | ||||
|
Session: 26.70: Posters B (Poster) on Tuesday in Chaired by Authors: Presenting Author: Prof Lorraine Sherr - UCL, United Kingdom |
||||
| Additional Authors: Dr Richard Harding, Dr Fiona Lampe, Ms Heather Leake-Date, Ms Sally Norwood, Prof Margaret Johnson, Dr Jane Anderson, Dr Sarah Zetler, Dr Martin Fisher, Dr Gilly Arthur, Dr Simon Edwards, | ||||
| Aim: This study was set up to examine adherence to antiretroviral treatment in a cohort of UK patients in London and the South East and to monitor full adherence, taking into consideration dose adherence, timing and circumstances within the measures and then exploring adherence implications | ||||
| Method / Issue: Consecutive attenders at 5 HIV clinics participated in a cross sectional questionnaire study. All patients who were not too ill to be approached and spoke sufficiently fluent English to complete the standardised inventories and were currently on treatment (n=502) were included (86% response rate). Adherence was measured by self recall over the preceding week with a notation of medication taking as well as adherence to time and special circumstance provisions. Quality of life, disclosure, risky behaviour and demographic information was also gathered. | ||||
| Results / Comments: 441 (79.1%) reported dose adherence +95%. However 42.8% had not taken their dose at the correct time, and 27.2% had not taken it under the correct circumstances, reducing full adherence from 79.1% to 41.5%. Comparisons of fully adherent dose+circumstance (41.5%), partially adherent dose only - (36.1%) and not adherent (22.4%) showed a significant effect for age (younger people | ||||
| Discussion: Previous studies overincluded people whose adherence was partial. Full and careful measurement of adherence reduces adherence rates dramatically. Combinations that avoid timing and circumstance requirements will enhance adherence. Interventions can be targeted at those who may find full adherence a challenge and a simple focus on dose adherence may generate an inaccurate picture. | ||||
| Go Back | ||||
