Amsterdam 2015
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| Abstract #2016 - "When I am 64" - Ageing and HIV | ||||
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Session: 51.1: "When I am 64" - Ageing and HIV (Parallel) on Friday @ 11.00-12.30 in C104 Chaired by Sarah Zetler, Mylene Fernet Authors: Presenting Author: Prof. Marco Pereira - University of Coimbra, Portugal |
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| Additional Authors: | ||||
| Aim: HIV infection has been historically considered a disease of young adults, however, adults aged 50 years and older represent now an increasing proportion of HIV/AIDS cases worldwide, including in Portugal. In this context, given the considerable burden associated with living with HIV, the topic of quality of life assessment has become increasingly relevant. The aims of this study were to compare the quality of life domains and specific facets of younger and middle-aged and older patients with HIV and to examine the sociodemographic, HIV-related and psychological factors associated with overall quality of life. | ||||
| Method / Issue: The sample of this prospective study consisted of 1194 patients infected with HIV, recruited from 10 Portuguese hospitals. Quality of life data were collected using the WHOQOL-HIV-Bref questionnaire. Participants also completed the Portuguese version of the Brief Symptom Inventory (BSI). | ||||
| Results / Comments: Of the 1194 patients, 185 (15.5%) were over 50 years old. Compared to younger patients, middle-aged and older patients living with HIV were more likely to be married/cohabiting or retired, to be unemployed or not currently working, to be more recently diagnosed with HIV and to report sexual transmission. Middle-aged and older patients reported significantly lower quality of life in Physical, Independence and Social relationships domains. Regarding the specific facets of quality of life, middle-aged and older patients reported significantly lower scores in 8 of the 29 facets. Among middle-aged and older patients, being currently employed and have fewer somatic and depressive symptoms were significantly associated with increased quality of life, explaining 44.1% of the total variance. In contrast, among younger patients, the factors that were associated with better overall quality of life were a higher level of education, being employed, being asymptomatic, having increased CD4+ T-cell count, being on cART, not having other co-infections, and having fewer somatic and depressive symptoms (R2 = .38). | ||||
| Discussion: Since an important feature of healthy ageing is the maintenance of quality of life, these data may provide potentially useful information for tailoring age-appropriate and effective interventions, in order to improve mental health and quality of life of middle-aged and older patients living with HIV. | ||||
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