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			| Abstract #2278  -  The next generation: Children and HIV in Eastern- and Southern Africa |  
					| Session: 38.3: The next generation: Children and HIV in Eastern- and Southern Africa (Parallel) on Thursday @ 14.30-16.00 in C202 Chaired by Lucie Cluver,
 Lisa Langhaug,
 Brighton Gwezera
 Authors:
 Presenting Author:   Prof Simon Gregson - Imperial College London, United Kingdom
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					| Aim: Cash transfers (CTs) can increase school enrolment and thereby reduce HIV incidence in adolescents in African populations. We investigate the role of reduced substance use as a mechanism through which CTs reduce HIV risk.
 
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					| Method / Issue: Associations between: (i) orphanhood and substance use (alcohol, recreational drugs, and smoking), (ii) substance use and sexual risk behaviours, and (iii) school enrolment and substance use, in 3,274 adolescents interviewed in a household survey in east Zimbabwe, were measured using multivariable regression.
 
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					| Results / Comments: 6.4%, 3.2% and 0.9% of males reported alcohol, recreational drug, and cigarette use. Few females (<1%) reported substance use. For males, drug use was more common in maternal orphans (4.9%) and double orphans (5.4%) than in non-orphans (2.8%). Substance use was positively associated with early sexual debut, number of sexual partners, and transactional sex. School enrolment was associated with lower substance use amongst male adolescents (2.7% versus 10.6%, p<0.001). Adjustment for substance abuse reduced the association between school enrolment and sexual experience, although the effect remained statistically significant.
 
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					| Discussion: Reduced substance abuse may contribute to reductions in adolescent HIV risk found in CT programmes.
 
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