Amsterdam 2015
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| Abstract #3410 - Poster 1 | ||||
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Session: 58.29: Poster 1 (Poster) on Tuesday in Chaired by Authors: Presenting Author: Dr Tristan Barber - Chelsea and Westminster NHS Foundation Trust, United Kingdom |
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| Additional Authors: Dr Kouassi Martin, Mr Brou Sylvain, | ||||
| Aim: This study aimed to determine the prevalence of HIV neurocognitive impairment in HIV infected men who have sex with men using a short battery of screening tests in routine clinical appointments. Those with suspected abnormalities were referred on for further assessment. The cohort was also followed up over time to look at evolving changes. | ||||
| Method / Issue: HIV-1 infected participants were recruited at three clinical sites in London during routine clinical visits. They could be clinician or self-referred and did not need to be symptomatic. They completed questionnaires on anxiety, depression, and memory. They were then screened using the Brief Neurocognitive Screen (BNCS) and International HIV Dementia Scale (IHDS). | ||||
| Results / Comments: Two hundred and five HIV infected subjects were recruited. Of these, 59 patients were excluded as having a mood disorder and 2 patients were excluded due to insufficient data, leaving 144 patients for analysis. One hundred and twenty four (86.1%) had a normal composite z score (within 1sd of mean) calculated for their scores on the three component tests of the BNCS. Twenty (13.9%) had an abnormal z score of which seven (35%) were symptomatic and thirteen (65%) asymptomatic. Current employment and previous educational level were significantly associated with BNCS scores. Of those referred onwards for diagnostic testing only one participant was found to have impairment likely related to HIV infection. Depression tended to improve between baseline and follow up but other parameters did not change significantly. | ||||
| Discussion: We were able to screen for mood disorders and cognitive impairment in routine clinical practice. We identified a high level of depression and anxiety in our cohort. Using short screening tests in clinic and an onward referral process for further testing we were not able to identify neurocognitive impairment in this cohort at levels consistent with published data. | ||||
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